Benzeneacetamide, N-[5-(1-methylethyl)-2-thiazolyl]-
BML-259
CAS: 267654-00-2
Molecular Formula: C14H16N2OS
Benzeneacetamide, N-[5-(1-methylethyl)-2-thiazolyl]- - Names and Identifiers
| Name | BML-259 |
| Synonyms | BML-259 CAY10554 2-phenyl-N-(5-propan-2-yl-1,3-thiazol-2-yl)acetamide Benzeneacetamide, N-[5-(1-methylethyl)-2-thiazolyl]- |
| CAS | 267654-00-2 |
Benzeneacetamide, N-[5-(1-methylethyl)-2-thiazolyl]- - Physico-chemical Properties
| Molecular Formula | C14H16N2OS |
| Molar Mass | 260.35 |
| Melting Point | 150-152℃ |
| Solubility | DMSO:15mg/ml |
| Appearance | White solid. |
| Color | white |
| Storage Condition | RT |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
| Use | BML-259 is a potent cyclin-dependent kinase 5 (Cdk5) inhibitor with IC50 of 64 and 98 nM for Cdk5 and Cdk2, respectively. |
Benzeneacetamide, N-[5-(1-methylethyl)-2-thiazolyl]- - Reference
| Reference Show more | 1. Kaźmierczak A, et al. A novel mechanism of non-Aβ component of Alzheimer's disease amyloid (NAC) neurotoxicity. Interplay between p53 protein and cyclin-dependent kinase 5 (Cdk5). Neurochem Int. 2011;58(2):206-214. |
Benzeneacetamide, N-[5-(1-methylethyl)-2-thiazolyl]- - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3.841 ml | 19.204 ml | 38.409 ml |
| 5 mM | 0.768 ml | 3.841 ml | 7.682 ml |
| 10 mM | 0.384 ml | 1.92 ml | 3.841 ml |
| 5 mM | 0.077 ml | 0.384 ml | 0.768 ml |
Last Update：2024-01-02 23:10:35
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CAS: 267654-00-2
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Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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CAS: 267654-00-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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